Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | HTR2C | P28335 | 2/20 | 0.50 |
| ▸ | HTR2B | P41595 | 2/20 | 0.50 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MC5R | P33032 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Clobenzorex SCHEMBL31080692 | 0.83 | LMNA (1.00) | LMNASIGMAR1POLBMAPK1ATM | |
| Clobenzorex SCHEMBL26720 | 0.83 | LMNA (1.00) | LMNASIGMAR1POLBMAPK1ATM | |
| SCHEMBL23023142 | 0.82 | SIGMAR1 (0.69) | LMNASIGMAR1ADRB2HTR2AHTR2C | |
| SCHEMBL13479679 | 0.82 | LMNA (0.74) | LMNASIGMAR1CASRPOLBMAPK1 | |
| Clobenzorex SCHEMBL1649957 | 0.81 | LMNA (0.94) | LMNASIGMAR1POLBMAPK1ATM | |
| SCHEMBL18769860 | 0.78 | ADRB2 (0.62) | SIGMAR1ADRB2HTR2AHTR2CHTR2B | |
| SCHEMBL13995787 | 0.77 | LMNA (0.71) | LMNASIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL19772457 | 0.75 | LMNA (0.68) | LMNAHTR2AHTR2CHTR2BCASR | |
| SCHEMBL12767657 | 0.75 | HTR2A (0.62) | SIGMAR1ADRB2HTR2AHTR2CHTR2B | |
| SCHEMBL10023024 | 0.75 | HTR2A (0.62) | SIGMAR1ADRB2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052890-A1 | 3-ARYLPROPYLAMINO NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-11-26 | — | — | WO | disclosed |