Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | MME | P08473 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8589579 | 0.86 | KMT2A (0.50) | LMNAKMT2AOPRK1 | |
| SCHEMBL8588155 | 0.83 | LMNA (0.57) | CYP19A1TAAR1LMNAOPRK1MME | |
| SCHEMBL8589191 | 0.83 | ALDH1A1 (0.43) | CYP19A1TAAR1LMNAMMEMAPK1 | |
| SCHEMBL8588129 | 0.83 | EPHX2 (0.44) | MME | |
| SCHEMBL8588435 | 0.82 | SIGMAR1 (0.51) | TAAR1LMNAOPRK1MAPK1OPRD1 | |
| SCHEMBL8588135 | 0.81 | CYP3A4 (0.51) | MAPK1 | |
| SCHEMBL8589150 | 0.81 | TAAR1 (0.40) | TAAR1OPRK1MMEOPRD1BACE1 | |
| SCHEMBL8590681 | 0.80 | ATM (0.51) | CYP19A1KMT2A | |
| SCHEMBL8589108 | 0.77 | CHRNA7 (0.42) | LMNAKMT2A | |
| SCHEMBL8587928 | 0.77 | DPP7 (0.47) | TAAR1LMNAMMEMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052890-A1 | 3-ARYLPROPYLAMINO NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-11-26 | — | — | WO | disclosed |