Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8586939 | 0.89 | LMNA (0.52) | LMNATAAR1FFAR1PNMTRAB9A | |
| SCHEMBL8588989 | 0.83 | CYP19A1 (0.43) | LMNACYP19A1MMETAAR1OPRK1 | |
| SCHEMBL8587928 | 0.83 | DPP7 (0.47) | LMNAMMETAAR1 | |
| SCHEMBL8588066 | 0.82 | S1PR3 (0.45) | MMETAAR1PNMT | |
| SCHEMBL8588435 | 0.82 | SIGMAR1 (0.51) | LMNATAAR1OPRK1 | |
| SCHEMBL8586524 | 0.81 | ACLY (0.43) | MMETAAR1ITGB1ITGA4OPRK1 | |
| SCHEMBL8588129 | 0.80 | EPHX2 (0.44) | MME | |
| SCHEMBL8590681 | 0.80 | ATM (0.51) | CYP19A1ITGA4ITGB7 | |
| SCHEMBL8586519 | 0.77 | LMNA (0.47) | LMNARAB9A | |
| SCHEMBL8589191 | 0.77 | ALDH1A1 (0.43) | LMNASMN1; SMN2CYP19A1MMETAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998052890-A1 | 3-ARYLPROPYLAMINO NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-11-26 | — | — | WO | disclosed |