Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 1/20 | 0.49 |
| ▸ | FAP | Q12884 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 6/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3105144 | 0.75 | HRH3 (0.47) | HRH3ALDH1A1KMT2AHTTSMN1; SMN2 | |
| SCHEMBL27666303 | 0.73 | TAS1R3 (0.55) | ALDH1A1KMT2ACYP1A2CCR1MEN1 | |
| SCHEMBL27666301 | 0.73 | TAS1R3 (0.55) | ALDH1A1KMT2ACYP1A2CCR1MEN1 | |
| SCHEMBL23507512 | 0.70 | CTSL (0.64) | PREPFAPHPGD | |
| Oxalic Acid SCHEMBL30439587 | 0.69 | MLYCD (0.55) | ALDH1A1KMT2AHTTSMN1; SMN2CYP1A2 | |
| SCHEMBL29772431 | 0.69 | MLYCD (0.58) | ALDH1A1KMT2ATSHRHTTSMN1; SMN2 | |
| SCHEMBL24998749 | 0.69 | MLYCD (0.58) | ALDH1A1KMT2ATSHRHTTSMN1; SMN2 | |
| SCHEMBL155518 | 0.69 | MLYCD (0.58) | ALDH1A1KMT2ATSHRHTTSMN1; SMN2 | |
| SCHEMBL3289063 | 0.69 | SLC6A3 (0.48) | PREPFAPALDH1A1KMT2ATSHR | |
| SCHEMBL2400798 | 0.69 | ALDH1A1 (0.47) | PREPFAPACEALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998039295-A1 | (R)N-(1-CYCLOPROPYLMETHYLPYRROLIDIN-2-YLMETHYL)BENZAMIDE AND ITS USE AS AN ANTIDIARRHOEAL | JOUVEINAL (FR) | 1998-09-11 | — | — | WO | disclosed |