SCHEMBL8592131

SCHEMBL8592131

Cc1c(CCO)[nH]c(=O)n(N)c1=O

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
GAA P10253 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
GLA P06280 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8592123 0.73 KDM4E (0.32) KDM4EKMT2A
SCHEMBL18518294 0.61 ALDH1A1 (0.43) ALDH1A1GAAKDM4EMEN1GLA
SCHEMBL10831986 0.56 KDM4E (0.43) ALDH1A1GAAKDM4E
SCHEMBL4315838 0.56 KDM4E (0.43) KDM4E
SCHEMBL3480363 0.54 ALDH1A1 (0.38) ALDH1A1KDM4EGLA
SCHEMBL22685276 0.52 ALDH1A1 (0.44) ALDH1A1GAAKDM4EMEN1GLA
SCHEMBL17490535 0.52 SLC9A1 (0.44) ALDH1A1GAAKDM4EMEN1GLA
SCHEMBL9617847 0.51 MAPT (0.44) ALDH1A1GAAKDM4EMEN1GLA
SCHEMBL8375956 0.51 ALDH1A1 (0.37) ALDH1A1GAAKDM4EMEN1GLA
SCHEMBL15492132 0.51 CSNK2A2 (0.34) ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10017555-A None JP disclosed
JP-H1017555-A 6-AMINO-5-METHYLURACIL DERIVATIVE MITSUI PETROCHEM IND LTD 1998-01-20 JP disclosed