Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 9/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145411 | 0.83 | TBXAS1 (0.56) | TBXAS1MAPTLMNATP53 | |
| SCHEMBL10851841 | 0.81 | TBXAS1 (0.46) | TBXAS1MAPTLMNATP53 | |
| SCHEMBL10859386 | 0.78 | HTT (0.42) | TBXAS1 | |
| SCHEMBL10856578 | 0.76 | TBXAS1 (0.56) | TBXAS1NAPRT | |
| SCHEMBL10858213 | 0.75 | AR (0.41) | — | |
| SCHEMBL8119538 | 0.71 | MTNR1A (0.66) | CLK1MTNR1AMTNR1B | |
| SCHEMBL10859377 | 0.71 | PTGFR (0.39) | TBXAS1LMNA | |
| SCHEMBL17888979 | 0.69 | ALDH1A1 (0.50) | — | |
| SCHEMBL8117069 | 0.69 | NR1D1 (0.43) | CLK1MAPTLMNAMTNR1AMTNR1B | |
| SCHEMBL10854472 | 0.68 | AR (0.41) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0662950-B1 | BENZENEALKANOIC ACIDS FOR CARDIOVASCULAR DISEASES | PFIZER LTD (GB) | 1998-01-14 | — | — | EP | claimed |