Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.30 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599316 | 0.77 | KDM4E (0.36) | ALDH1A1KDM4ELMNAHTTCYP3A4 | |
| SCHEMBL8599306 | 0.77 | ATG4B (0.43) | ALDH1A1HTTCYP3A4CYP2C19KMT2A | |
| SCHEMBL8595645 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KDM4ELMNAHTTCYP3A4 | |
| SCHEMBL8595119 | 0.76 | ALDH1A1 (0.39) | ALDH1A1KDM4ELMNAHTTCYP3A4 | |
| SCHEMBL8597055 | 0.76 | ALDH1A1 (0.36) | ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8566366 | 0.74 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNACYP3A4KMT2A | |
| SCHEMBL8563141 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KDM4ELMNACYP3A4CYP2D6 | |
| SCHEMBL8564125 | 0.73 | ALDH1A1 (0.33) | ALDH1A1LMNAHTTCYP3A4MAPT | |
| SCHEMBL8600107 | 0.73 | KDM4E (0.36) | ALDH1A1KDM4ELMNAHTTCYP3A4 | |
| SCHEMBL8596319 | 0.72 | ALDH1A1 (0.32) | ALDH1A1HTTCYP2C19KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |