Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563141 | 0.86 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTCYP3A4BLM | |
| SCHEMBL8564125 | 0.85 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL8566803 | 0.78 | ALOX15 (0.44) | ALDH1A1LMNAMAPTCYP3A4KMT2A | |
| SCHEMBL8568828 | 0.76 | TDP1 (0.48) | ALDH1A1MAPTCYP3A4KMT2AMEN1 | |
| SCHEMBL8562235 | 0.76 | TDP1 (0.48) | ALDH1A1LMNAMAPTCYP3A4KMT2A | |
| SCHEMBL8559950 | 0.75 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTCYP3A4KMT2A | |
| SCHEMBL8599052 | 0.75 | HTT (0.40) | ALDH1A1LMNA | |
| SCHEMBL8599306 | 0.74 | ATG4B (0.43) | ALDH1A1MAPTCYP3A4KMT2ANPC1 | |
| SCHEMBL8596069 | 0.74 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTCYP3A4KMT2A | |
| SCHEMBL8562881 | 0.74 | MAPK1 (0.37) | ALDH1A1MAPTNPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |