Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597941 | 0.78 | HTR2A (0.43) | ALOX15HPGDALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8566566 | 0.78 | CYP1A2 (0.52) | ATG4BHPGDCYP1A2POLBCYP3A4 | |
| SCHEMBL8596069 | 0.77 | ALDH1A1 (0.35) | ATG4BHPGDPOLBCYP3A4CYP2C19 | |
| SCHEMBL8598112 | 0.77 | SMN1; SMN2 (0.43) | ATG4BMAPK1HSD17B10ALOX15HPGD | |
| SCHEMBL8597304 | 0.77 | ALOX15 (0.43) | ATG4BMAPK1HSD17B10ALOX15HPGD | |
| SCHEMBL8600033 | 0.76 | HPGD (0.50) | ATG4BHPGDCYP1A2POLBCYP3A4 | |
| SCHEMBL8603087 | 0.76 | HCAR3 (0.42) | ATG4BCYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL8563141 | 0.74 | ALDH1A1 (0.44) | MAPK1HSD17B10ALOX15HPGDCYP1A2 | |
| SCHEMBL8566366 | 0.74 | ALDH1A1 (0.42) | ALOX15HPGDPOLBCYP3A4MAPT | |
| SCHEMBL8564125 | 0.73 | ALDH1A1 (0.33) | MAPK1HSD17B10ALOX15HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |