Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8563141 | 0.85 | ALDH1A1 (0.44) | ALDH1A1MAPK1CYP1A2GAALMNA | |
| SCHEMBL8566366 | 0.85 | ALDH1A1 (0.42) | ALDH1A1GAALMNAALOX15CYP3A4 | |
| SCHEMBL8566803 | 0.77 | ALOX15 (0.44) | ALDH1A1MAPK1GAALMNACA12 | |
| SCHEMBL15081394 | 0.74 | SMN1; SMN2 (0.39) | ALDH1A1CYP1A2LMNATDP1SMN1; SMN2 | |
| SCHEMBL8562235 | 0.74 | TDP1 (0.48) | ALDH1A1MAPK1LMNAALOX15CYP3A4 | |
| SCHEMBL8568828 | 0.74 | TDP1 (0.48) | ALDH1A1MAPK1ALOX15CYP3A4TDP1 | |
| SCHEMBL8597941 | 0.74 | HTR2A (0.43) | ALDH1A1LMNAALOX15HPGDSMN1; SMN2 | |
| SCHEMBL8599426 | 0.74 | ESR1 (0.48) | ALDH1A1MAPK1CYP1A2LMNACYP3A4 | |
| SCHEMBL8559950 | 0.74 | ALDH1A1 (0.39) | ALDH1A1CYP1A2GAALMNACYP3A4 | |
| SCHEMBL8599306 | 0.73 | ATG4B (0.43) | ALDH1A1MAPK1CYP1A2ALOX15CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |