Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | KDM5C | P41229 | 3/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16761792 | 0.87 | ECE1 (0.41) | ECE1MLYCDNPSR1KDM4EEPHX2 | |
| SCHEMBL20556419 | 0.87 | EPHX2 (0.51) | KDM4EEPHX2MEN1GAAKMT2A | |
| SCHEMBL12997717 | 0.86 | MEN1 (0.42) | KDM4EEPHX2MEN1GAAKMT2A | |
| SCHEMBL8531447 | 0.86 | TSHR (0.46) | MLYCDKDM4EEPHX2KMT2AALDH1A1 | |
| SCHEMBL13143977 | 0.85 | RECQL (0.47) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL5617349 | 0.85 | MAOA (0.38) | ECE1NPSR1PHF8KDM2AKDM4E | |
| SCHEMBL29594603 | 0.84 | TLR2 (0.41) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL947583 | 0.84 | CASP2 (0.48) | MLYCDEPHX2GAARECQLFAAH | |
| SCHEMBL21038130 | 0.84 | EPHX2 (0.43) | ECE1MLYCDNPSR1EPHX2MEN1 | |
| SCHEMBL4394882 | 0.84 | MEN1 (0.53) | NPSR1PHF8KDM2AKDM4EKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065958-A1 | METHOD OF TREATING CONTRAST-INDUCED NEPHROPATHY | NOVARTIS AG (CH) | 2012-05-24 | — | — | WO | disclosed |
| US-20100305131-A1 | Substituted Aminopropionic Derivatives as Neprilysin inhibitors | NOVARTIS AG (CH) | 2010-12-02 | — | — | US | disclosed |
| CN-101225094-A | Anthraquinones tetracyclic compound having anticancer activity | TIANJIN HEMEI BIOTECHNOLOGY CO (CN) | 2008-07-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305131-A1 | Substituted Aminopropionic Derivatives as Neprilysin inhibitors | MME, AGTR1, REN | ECE1 13/4885MLYCD 4677/4885NPSR1 45/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.