Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601221 | 0.81 | HPGD (0.46) | HSD17B10HPGDCYP2C9CYP1A2ALDH1A1 | |
| SCHEMBL8648411 | 0.73 | ALDH1A1 (0.45) | HSD17B10HPGDCYP2C9CYP1A2ALDH1A1 | |
| SCHEMBL8602599 | 0.72 | PIK3C2B (0.40) | CYP2C9CYP1A2ALDH1A1APEX1CYP2C19 | |
| SCHEMBL8603673 | 0.72 | ALDH1A1 (0.45) | HSD17B10HPGDCYP2C9CYP1A2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL8603670 | 0.72 | ALDH1A1 (0.43) | HSD17B10HPGDCYP2C9CYP1A2ALDH1A1 | |
| SCHEMBL8600239 | 0.69 | TSHR (0.41) | HSD17B10HPGDCYP2C9CYP1A2ALDH1A1 | |
| SCHEMBL8599899 | 0.68 | TP53 (0.44) | HSD17B10HPGDCYP2C9CYP1A2ALDH1A1 | |
| SCHEMBL8600493 | 0.68 | DCTPP1 (0.44) | HSD17B10HPGDALDH1A1KDM4ETSHR | |
| SCHEMBL9483999 | 0.67 | THRB (0.44) | HPGDALDH1A1KDM4ELMNANPSR1 | |
| SCHEMBL11760442 | 0.67 | TP53 (0.47) | ALDH1A1LMNAKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |