Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.71 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL2590009 | 0.85 | TDP1 (0.83) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| Propylene Glycol SCHEMBL458673 | 0.85 | — | — | |
| Propylene Glycol SCHEMBL83155 | 0.85 | — | — | |
| Propylene Glycol SCHEMBL15463578 | 0.85 | TDP1 (0.83) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| Propylene Glycol SCHEMBL28578 | 0.84 | — | — | |
| Propylene Glycol SCHEMBL3535 | 0.84 | — | — | |
| Propylene Glycol SCHEMBL161401 | 0.84 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| Propylene Glycol SCHEMBL7522896 | 0.84 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| Propylene Glycol SCHEMBL15864609 | 0.84 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| Propylene Glycol SCHEMBL724028 | 0.84 | TDP1 (1.00) | TDP1TSHRALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099953-B1 | STORAGE STABLE COMPOSITION OF PARTIAL AND/OR COMPLETE CONDENSATE OF HYDROLYZABLE ORGANOFUNCTIONAL SILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2019-04-03 | — | — | EP | claimed |
| US-8609755-B2 | Storage stable composition of partial and/or complete condensate of hydrolyzable organofunctional silane | MOMENTIVE PERFOMANCE MATERIALS INC. (US) | 2013-12-17 | — | — | US | claimed |
| EP-2382277-A1 | SILANE COATING COMPOSITIONS CONTAINING SILICON-BASED POLYETHER COPOLYMERS, METHODS FOR COATING METAL SURFACES AND ARTICLES MADE THEREFROM | Momentive Performance Materials Inc. (US) | 2011-11-02 | — | — | EP | claimed |
| WO-2010080965-A1 | SILANE COATING COMPOSITIONS CONTAINING SILICON-BASED POLYETHER COPOLYMERS, METHODS FOR COATING METAL SURFACES AND ARTICLES MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS (US) | 2010-07-15 | — | — | WO | claimed |
| US-20100178521-A1 | SILANE COATING COMPOSITIONS CONTAINING SILICON-BASED POLYETHER COPOLYMERS, METHODS FOR COATING METAL SURFACES AND ARTICLESMADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2010-07-15 | — | — | US | claimed |
| EP-2099953-A2 | STORAGE STABLE COMPOSITION OF PARTIAL AND/OR COMPLETE CONDENSATE OF HYDROLYZABLE ORGANOFUNCTIONAL SILANE | Momentive Performance Materials Inc. (US) | 2009-09-16 | — | — | EP | claimed |
| WO-2008041976-A2 | STORAGE STABLE COMPOSITION OF PARTIAL AND/OR COMPLETE CONDENSATE OF HYDROLYZABLE ORGANOFUNCTIONAL SILANE | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-04-10 | — | — | WO | claimed |
| US-20070090329-A1 | Storage stable composition of partial and/or complete condensate of hydrolyzable organofunctional silane | MOMENTIVE PERFORMANCE MATERIALS INC. | 2007-04-26 | — | — | US | claimed |
| EP-3476876-B1 | PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2023-08-09 | — | — | EP | disclosed |
| US-10570519-B2 | Conversion coating composition comprising a dye and a method for coating a metal surface with said conversion coating composition | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2020-02-25 | — | — | US | disclosed |
| EP-3024865-B1 | MOISTURE CURABLE COMPOSITIONS WITH ENHANCED ELONGATION AND TEAR PROPERTIES | MOMENTIVE PERFORMANCE MAT INC (US) | 2019-10-09 | — | — | EP | disclosed |
| EP-3094661-B1 | COMPOSITIONS WITH ENHANCED FLEXIBILITY | MOMENTIVE PERFORMANCE MAT INC (US) | 2019-06-19 | — | — | EP | disclosed |
| EP-3476876-A1 | PROCESS FOR THE PREPARATION OF SILYLATED POLYURETHANE POLYMERS USING TITANIUM-CONTAINING AND ZIRCONIUM-CONTAINING CATALYSTS | Momentive Performance Materials Inc. (US) | 2019-05-01 | — | — | EP | disclosed |
| EP-2099953-B1 | STORAGE STABLE COMPOSITION OF PARTIAL AND/OR COMPLETE CONDENSATE OF HYDROLYZABLE ORGANOFUNCTIONAL SILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2019-04-03 | — | — | EP | disclosed |
| US-20070191558-A1 | Olefin polymerization procatalyst compositions and method of preparation | GONZALEZ KELLY A | 2007-08-16 | — | — | US | disclosed |
| EP-1802694-A1 | AQUEOUS DEVELOPABLE BENZOCYCLOBUTENE-BASED POLYMER COMPOSITION AND METHOD OF USE OF SUCH COMPOSITIONS | Dow Gloval Technologies Inc. (US) | 2007-07-04 | — | — | EP | disclosed |
| US-20070090329-A1 | Storage stable composition of partial and/or complete condensate of hydrolyzable organofunctional silane | MOMENTIVE PERFORMANCE MATERIALS INC. | 2007-04-26 | — | — | US | disclosed |
| EP-1735353-A1 | OLEFIN POLYMERIZATION PROCATALYST COMPOSITIONS AND METHOD OF PREPARATION | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2006044338-A1 | AQUEOUS DEVELOPABLE BENZOCYCLOBUTENE-BASED POLYMER COMPOSITION AND METHOD OF USE OF SUCH COMPOSITIONS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-04-27 | — | — | WO | disclosed |
| WO-2005103094-A1 | OLEFIN POLYMERIZATION PROCATALYST COMPOSITIONS AND METHOD OF PREPARATION | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2005-11-03 | — | — | WO | disclosed |