Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599849 | 0.88 | LMNA (0.33) | HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL8603149 | 0.86 | MAPT (0.41) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL8603214 | 0.85 | LMNA (0.38) | ALDH1A1LMNASMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL8599272 | 0.85 | APP (0.39) | HPGDMAPTLMNASMN1; SMN2CA12 | |
| SCHEMBL4682474 | 0.84 | ALDH1A1 (0.36) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL8604182 | 0.83 | PPOX (0.32) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL8350503 | 0.82 | ESR1 (0.39) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 | |
| SCHEMBL8601390 | 0.81 | CYP19A1 (0.36) | HPGDMAPTLMNASMN1; SMN2GAA | |
| SCHEMBL8603053 | 0.81 | MAPT (0.37) | ALDH1A1MAPTLMNAKDM4EHSD17B10 | |
| SCHEMBL9040591 | 0.80 | DHODH (0.39) | ALDH1A1HPGDMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |