Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599215 | 0.88 | ALDH1A1 (0.38) | LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL8603149 | 0.85 | MAPT (0.41) | LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL8603214 | 0.84 | LMNA (0.38) | LMNASMN1; SMN2 | |
| SCHEMBL8599272 | 0.84 | APP (0.39) | LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL8604182 | 0.82 | PPOX (0.32) | LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL8350503 | 0.81 | ESR1 (0.39) | LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL8603218 | 0.81 | MAPT (0.32) | LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL8601390 | 0.80 | CYP19A1 (0.36) | LMNAMAPTHPGDSMN1; SMN2 | |
| SCHEMBL8603053 | 0.80 | MAPT (0.37) | LMNAMAPT | |
| SCHEMBL8601360 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |