Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600809 | 0.84 | CA2 (0.44) | CA2CHRNA7MAPTCYP3A4CYP2C19 | |
| SCHEMBL8600765 | 0.83 | CA2 (0.43) | CA2CHRNA7MAPTLMNANPC1 | |
| SCHEMBL4444185 | 0.83 | CA2 (0.43) | CA2CHRNA7MAPTLMNANPC1 | |
| SCHEMBL8596068 | 0.83 | CA2 (0.43) | CA2CHRNA7MAPTLMNANPC1 | |
| SCHEMBL8599290 | 0.80 | CHRNA7 (0.42) | CA2POLBCHRNA7MAPTLMNA | |
| SCHEMBL4143774 | 0.79 | SIGMAR1 (0.48) | KMT2AMEN1CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL8598275 | 0.73 | CHRNA7 (0.39) | CA2CHRNA7MAPTNPC1RAB9A | |
| SCHEMBL613806 | 0.72 | POLB (0.51) | POLBALDH1A1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL6311972 | 0.71 | ALDH1A1 (0.46) | ALDH1A1KMT2ACHRNA7KDM4EMEN1 | |
| SCHEMBL615305 | 0.70 | OPRM1 (0.53) | ALDH1A1KMT2ASMN1; SMN2MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641791-B1 | NOVEL BENZOTHIOPHENE DERIVATIVE | TEIKOKU HORMONE MFG CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5472962-A | Antiestrogenic agents | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1995-12-05 | — | — | US | disclosed |
| EP-0641791-A1 | NOVEL BENZOTHIOPHENE DERIVATIVE | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |