Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8596068 | 0.85 | CA2 (0.43) | MAPTNPC1RAB9ACHRNA7CA2 | |
| SCHEMBL4444185 | 0.85 | CA2 (0.43) | MAPTNPC1RAB9ACHRNA7CA2 | |
| SCHEMBL8600765 | 0.85 | CA2 (0.43) | MAPTNPC1RAB9ACHRNA7CA2 | |
| SCHEMBL8600809 | 0.83 | CA2 (0.44) | MAPTNPC1RAB9ACYP3A4CYP1A2 | |
| SCHEMBL8599290 | 0.71 | CHRNA7 (0.42) | MAPTNPC1RAB9ACYP3A4CYP1A2 | |
| SCHEMBL13885724 | 0.70 | ALDH1A1 (0.51) | MAPTKMT2ANPC1RAB9ATP53 | |
| SCHEMBL18911113 | 0.70 | HRH3 (0.57) | MAPTKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8598275 | 0.70 | CHRNA7 (0.39) | MAPTNPC1RAB9ACHRNA7CA2 | |
| SCHEMBL5534564 | 0.69 | ALDH1A1 (0.50) | MAPTKMT2ANPC1RAB9ATP53 | |
| SCHEMBL8598239 | 0.69 | CA2 (0.39) | MAPTKMT2ANPC1RAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641791-B1 | NOVEL BENZOTHIOPHENE DERIVATIVE | TEIKOKU HORMONE MFG CO LTD (JP) | 1998-01-28 | — | — | EP | disclosed |
| US-5472962-A | Antiestrogenic agents | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1995-12-05 | — | — | US | disclosed |
| EP-0641791-A1 | NOVEL BENZOTHIOPHENE DERIVATIVE | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |