SCHEMBL8601000

SCHEMBL8601000

CCCCCN1CC=C2C(=O)N=c3ccccc3=C21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.33
KMT2A Q03164 2/20 0.32
LMNA P02545 1/20 0.32
MAPT P10636 1/20 0.32
CCR6 P51684 1/20 0.32
ALDH1A1 P00352 3/20 0.32
ALDH2 P05091 1/20 0.32
ALDH3A1 P30838 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2D6 P10635 1/20 0.32
CYP2C19 P33261 1/20 0.32
CNR2 P34972 4/20 0.32
CES1 P23141 2/20 0.32
CDC25A P30304 1/20 0.32
CNR1 P21554 1/20 0.32
GBA1 P04062 1/20 0.32
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
HTT P42858 1/20 0.31
FAAH O00519 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28041004 0.66 CTSV (0.37) ATMMAPTALDH1A1
SCHEMBL17022467 0.62 MAPT (0.45) ATMKMT2AMAPTALDH1A1CES1
SCHEMBL10502356 0.61 ATM (0.39) ATMKMT2ALMNAMAPTCCR6
SCHEMBL7692535 0.61 CGAS (0.41) ATMKMT2ALMNAMAPTCCR6
SCHEMBL9139763 0.61 ATM (0.41) ATMKMT2ALMNAMAPTCCR6
SCHEMBL3520478 0.60 ATM (0.38) ATMKMT2ALMNAMAPTCCR6
SCHEMBL28890950 0.60 ALDH1A1 (0.38) ATMKMT2ALMNAMAPTCCR6
SCHEMBL16370586 0.60 GBA1 (0.41) MAPTALDH1A1ALDH2ALDH3A1CES1
SCHEMBL5712077 0.60 ALDH1A1 (0.53) KMT2AMAPTALDH1A1ALDH2ALDH3A1
SCHEMBL28066319 0.59 ALDH1A1 (0.33) KMT2ALMNAALDH1A1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0853622-A1 PROCESS FOR PREPARING 1-ARYL-4-OXOPYRROLO 3,2-c]QUINOLINE DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1998-07-22 EP claimed
WO-1997044342-A1 PROCESS FOR PREPARING 1-ARYL-4-OXOPYRROLO[3,2-c]QUINOLINE DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1997-11-27 WO claimed
EP-0853622-A1 PROCESS FOR PREPARING 1-ARYL-4-OXOPYRROLO 3,2-c]QUINOLINE DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1998-07-22 EP disclosed
EP-0853622-A1 PROCESS FOR PREPARING 1-ARYL-4-OXOPYRROLO 3,2-c]QUINOLINE DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1998-07-22 EP disclosed
WO-1997044342-A1 PROCESS FOR PREPARING 1-ARYL-4-OXOPYRROLO[3,2-c]QUINOLINE DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1997-11-27 WO disclosed
WO-1997044342-A1 PROCESS FOR PREPARING 1-ARYL-4-OXOPYRROLO[3,2-c]QUINOLINE DERIVATIVES KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 1997-11-27 WO disclosed