Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603224 | 0.77 | PDE4A (0.46) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8601171 | 0.77 | NR1D1 (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8601087 | 0.77 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1554928 | 0.73 | SLC22A12 (0.44) | PDE4APDE4BPDE4CPDE4DPTGER4 | |
| SCHEMBL8602159 | 0.72 | BRD4 (0.41) | PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL8571276 | 0.72 | SLC22A12 (0.44) | PDE4APDE4BPDE4CPDE4DPTGER4 | |
| SCHEMBL8600001 | 0.71 | CNR1 (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1554768 | 0.70 | ALDH1A1 (0.43) | PDE4APDE4BPDE4CPDE4DPTGER4 | |
| SCHEMBL8669588 | 0.70 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8599642 | 0.70 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998005327-A1 | SUBSTITUTED AROMATIC COMPOUNDS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1998-02-12 | — | — | WO | disclosed |