Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.32 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8600214 | 0.98 | PPOX (0.44) | PPOXL3MBTL1ALDH1A1TDP1LMNA | |
| SCHEMBL8600830 | 0.88 | PPOX (0.51) | PPOXL3MBTL1ALDH1A1TDP1LMNA | |
| SCHEMBL8598539 | 0.84 | ELANE (0.38) | L3MBTL1ALDH1A1TDP1LMNATSHR | |
| SCHEMBL8603603 | 0.83 | MAPT (0.39) | PPOXL3MBTL1ALDH1A1LMNATSHR | |
| SCHEMBL8598865 | 0.83 | PPOX (0.37) | PPOX | |
| SCHEMBL8599592 | 0.82 | PPOX (0.38) | PPOXALDH1A1LMNA | |
| SCHEMBL8600272 | 0.82 | ALDH1A1 (0.54) | PPOXL3MBTL1ALDH1A1TDP1LMNA | |
| SCHEMBL8598193 | 0.81 | ELANE (0.39) | L3MBTL1ALDH1A1TDP1LMNATSHR | |
| SCHEMBL8599137 | 0.81 | KDM4E (0.42) | PPOXALDH1A1TDP1TSHRGAA | |
| SCHEMBL8603664 | 0.81 | SMN1; SMN2 (0.40) | PPOXL3MBTL1ALDH1A1TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |