Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPOX | P50336 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599592 | 0.89 | PPOX (0.38) | MAPTPPOXSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8600830 | 0.88 | PPOX (0.51) | MAPTMEN1KMT2AL3MBTL1PPOX | |
| SCHEMBL8599137 | 0.88 | KDM4E (0.42) | KMT2APPOXALDH1A1KDM4EGAA | |
| SCHEMBL8598865 | 0.87 | PPOX (0.37) | PPOXHPGDCYP1A2GLACYP3A4 | |
| SCHEMBL8602458 | 0.85 | PPOX (0.44) | MAPTMEN1KMT2APPOXSMN1; SMN2 | |
| SCHEMBL8600214 | 0.85 | PPOX (0.44) | L3MBTL1PPOXSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8601518 | 0.83 | PPOX (0.45) | MAPTPPOXSMN1; SMN2GAAHPGD | |
| SCHEMBL8601614 | 0.83 | PPOX (0.43) | L3MBTL1PPOXALDH1A1GAATSHR | |
| SCHEMBL8603030 | 0.82 | CUL4A (0.40) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8579591 | 0.82 | PPOX (0.38) | MAPTMEN1KMT2APPOXALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |