Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8603603 | 0.89 | MAPT (0.39) | PPOXHPGDCYP1A2GLACYP3A4 | |
| SCHEMBL8600830 | 0.87 | PPOX (0.51) | PPOXHPGDKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8599137 | 0.86 | KDM4E (0.42) | PPOXHPGDCYP1A2GLACYP3A4 | |
| SCHEMBL8598865 | 0.86 | PPOX (0.37) | PPOXHPGDCYP1A2GLACYP3A4 | |
| SCHEMBL8602458 | 0.84 | PPOX (0.44) | PPOXHPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8600214 | 0.84 | PPOX (0.44) | PPOXHPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8579591 | 0.83 | PPOX (0.38) | PPOXHPGDCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL8599624 | 0.83 | CUL4A (0.31) | MAPT | |
| SCHEMBL8601518 | 0.82 | PPOX (0.45) | PPOXHPGDSMN1; SMN2LMNAMAPT | |
| SCHEMBL8601614 | 0.82 | PPOX (0.43) | PPOXALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626370-B1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL CO (JP) | 1998-02-11 | — | — | EP | disclosed |
| EP-0626370-A1 | Process for producing aromatic isothiocyanate derivatives | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1994-11-30 | — | — | EP | disclosed |