Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597440 | 0.87 | KDM4E (0.40) | ALDH1A1KDM4EPTGESMEN1KMT2A | |
| SCHEMBL8571701 | 0.85 | TAS1R3 (0.42) | ALDH1A1KDM4ETAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8599169 | 0.84 | PIK3CD (0.39) | ALDH1A1KDM4EPTGESMEN1KMT2A | |
| SCHEMBL8595161 | 0.84 | PTGES (0.42) | ALDH1A1KDM4EPTGESTP53MAPT | |
| SCHEMBL8599596 | 0.82 | LMNA (0.40) | ALDH1A1KDM4EPTGESMEN1KMT2A | |
| SCHEMBL8668515 | 0.80 | S1PR2 (0.38) | TAS1R3TAS1R1TAS1R2PTGESMEN1 | |
| SCHEMBL8602578 | 0.78 | RAB9A (0.43) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL8599561 | 0.78 | KDM4E (0.44) | ALDH1A1KDM4EKMT2AMAPT | |
| SCHEMBL8602012 | 0.75 | DCTPP1 (0.42) | ALDH1A1KDM4EKMT2AHTTMAPT | |
| SCHEMBL8600749 | 0.74 | MEN1 (0.40) | ALDH1A1KDM4ETAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |