Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.37 |
| ▸ | ITGAV | P06756 | 2/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.37 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668515 | 0.85 | S1PR2 (0.38) | MMP2S1PR2HTTLMNATSHR | |
| SCHEMBL8597757 | 0.85 | L3MBTL1 (0.46) | MMP2S1PR2HTTLMNASMN1; SMN2 | |
| SCHEMBL8597525 | 0.85 | KMT2A (0.41) | MMP2HTTLMNATSHRSMN1; SMN2 | |
| SCHEMBL8569083 | 0.85 | MMP2 (0.43) | MMP2HTTLMNATSHRSMN1; SMN2 | |
| SCHEMBL8597093 | 0.84 | MMP2 (0.42) | MMP2HTTLMNATSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8603024 | 0.84 | POLB (0.41) | MMP2HTTLMNATSHRSMN1; SMN2 | |
| SCHEMBL8601626 | 0.83 | MAPT (0.47) | MMP2HTTLMNATSHRSMN1; SMN2 | |
| SCHEMBL8602533 | 0.82 | MMP2 (0.41) | MMP2S1PR2HTTLMNATSHR | |
| SCHEMBL8603067 | 0.82 | L3MBTL1 (0.45) | MMP2S1PR2HTTLMNASMN1; SMN2 | |
| SCHEMBL8597593 | 0.82 | MMP2 (0.42) | MMP2HTTLMNATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |