Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.35 |
| ▸ | ITGAV | P06756 | 2/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.35 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8599596 | 0.90 | LMNA (0.40) | S1PR2MMP2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8571701 | 0.86 | TAS1R3 (0.42) | TAS1R3TAS1R1TAS1R2MMP2MEN1 | |
| SCHEMBL8602955 | 0.85 | MMP2 (0.43) | S1PR2MMP2MEN1KMT2ARAB9A | |
| SCHEMBL8597757 | 0.83 | L3MBTL1 (0.46) | S1PR2MMP2MEN1KMT2ARAB9A | |
| SCHEMBL8602578 | 0.83 | RAB9A (0.43) | MMP2MEN1KMT2ARAB9AHTT | |
| SCHEMBL8599822 | 0.80 | ALDH1A1 (0.37) | TAS1R3TAS1R1TAS1R2MMP2MEN1 | |
| SCHEMBL8603067 | 0.80 | L3MBTL1 (0.45) | S1PR2MMP2MEN1KMT2ARAB9A | |
| SCHEMBL8600307 | 0.76 | TP53 (0.44) | MMP2SMN1; SMN2HTTL3MBTL1TYK2 | |
| SCHEMBL8600749 | 0.73 | MEN1 (0.40) | TAS1R3TAS1R1TAS1R2MMP2MEN1 | |
| SCHEMBL8597525 | 0.72 | KMT2A (0.41) | MMP2MEN1KMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |