Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7597268 | 0.84 | PLK1 (0.43) | POLBADAMTS5PLK1 | |
| SCHEMBL3717367 | 0.83 | POLB (0.50) | POLBGAAPLK1MAPTMEN1 | |
| SCHEMBL7604367 | 0.82 | ADAMTS5 (0.38) | POLBADAMTS5CNR2GAATHRA | |
| SCHEMBL8598123 | 0.76 | HDAC1 (0.36) | POLBADAMTS5CNR2GAAMAPT | |
| Squaric Acid Dibutyl Ester SCHEMBL56180 | 0.74 | CYP3A4 (0.44) | THRATHRBMAPTALDH1A1 | |
| SCHEMBL7597357 | 0.73 | ADAMTS5 (0.38) | POLBADAMTS5CNR2GAATHRA | |
| SCHEMBL7602487 | 0.71 | ADAMTS5 (0.37) | POLBADAMTS5GAATHRATHRB | |
| Squaric Acid Dibutyl Ester SCHEMBL2304620 | 0.70 | THRA (0.36) | POLBTHRATHRBMAPTALDH1A1 | |
| SCHEMBL9749015 | 0.70 | CCNE2 (0.42) | ADAMTS5GAAMAPTMEN1ALDH1A1 | |
| SCHEMBL9749261 | 0.70 | ADAMTS5 (0.36) | POLBADAMTS5GAATHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763474-A | SMOOTH MUSCLE RELAXANTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-06-09 | — | — | US | disclosed |