Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | EIF4A3 | P38919 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 3/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20667351 | 0.80 | ALDH1A1 (0.58) | KIF11EIF4A3HTR1DAURKADAPK3 | |
| SCHEMBL8602948 | 0.77 | RXFP1 (0.52) | KIF11HTR2AALDH1A1PSMD14GAA | |
| SCHEMBL8601195 | 0.76 | KMT2A (0.38) | LMNAALDH1A1GAAKDM4E | |
| SCHEMBL8600852 | 0.76 | RHEB (0.36) | HTR1DHTR1BHTR2ALMNAALDH1A1 | |
| SCHEMBL8601909 | 0.75 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL83970 | 0.75 | AHR (0.50) | KIF11EIF4A3ALDH1A1TRPA1PTGS2 | |
| SCHEMBL8084300 | 0.74 | HTR3E (0.45) | HTR1DHTR1BHTR2AALDH1A1PSMD14 | |
| SCHEMBL8603706 | 0.73 | TYR (0.53) | HTR2ALMNAALDH1A1HTTPSMD14 | |
| SCHEMBL8604154 | 0.73 | KDM4E (0.41) | ALDH1A1PSMD14GAAKDM4E | |
| SCHEMBL8603460 | 0.73 | KMT2A (0.58) | GSK3BDYRK1AHTR2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |