Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8601909 | 0.83 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL8599686 | 0.81 | AR (0.43) | KDM4EARALDH1A1HSD17B10ALOX15 | |
| SCHEMBL8602948 | 0.76 | RXFP1 (0.52) | KDM4EALDH1A1HSD17B10ALOX15HPGD | |
| SCHEMBL8603563 | 0.75 | PARP1 (0.39) | KDM4EALDH1A1HSD17B10TSHRCYP3A4 | |
| SCHEMBL827584 | 0.73 | AHR (0.50) | KDM4EALDH1A1HSD17B10ALOX15TSHR | |
| SCHEMBL31084784 | 0.73 | AHR (0.50) | KDM4EALDH1A1HSD17B10ALOX15TSHR | |
| SCHEMBL8604156 | 0.73 | KIF11 (0.47) | KDM4EALDH1A1GAAPSMD14 | |
| SCHEMBL8084300 | 0.73 | HTR3E (0.45) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL8603706 | 0.72 | TYR (0.53) | KDM4EALDH1A1HSD17B10ALOX15HPGD | |
| SCHEMBL22372423 | 0.72 | AR (0.49) | KDM4EARIP6K1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |