Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12663454 | 0.78 | ALDH1A1 (0.41) | RXFP1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL8084300 | 0.77 | HTR3E (0.45) | RXFP1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL8604156 | 0.77 | KIF11 (0.47) | ALDH1A1KDM4EGAAHTR2AKIF11 | |
| SCHEMBL8603706 | 0.76 | TYR (0.53) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL12663392 | 0.76 | ALDH1A1 (0.63) | RXFP1ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL8603460 | 0.76 | KMT2A (0.58) | RXFP1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL8604154 | 0.76 | KDM4E (0.41) | ALDH1A1KDM4EMAPTHPGDALOX15 | |
| SCHEMBL8600219 | 0.73 | MAOA (0.43) | RXFP1ALDH1A1KDM4EMAPTKIF11 | |
| SCHEMBL8600177 | 0.73 | MAOA (0.46) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL8601195 | 0.72 | KMT2A (0.38) | RXFP1ALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |