Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR1E | P28566 | 1/20 | 0.33 |
| ▸ | HTR1F | P30939 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084300 | 0.83 | HTR3E (0.45) | RHEBHTR3EHTR3BHTR1AHTR1D | |
| SCHEMBL8604156 | 0.76 | KIF11 (0.47) | LMNAHIF1AHTR1DHTR1BHTR2A | |
| SCHEMBL7673837 | 0.76 | MEN1 (0.46) | LMNACYP1A2CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL13230543 | 0.74 | AHR (0.47) | LMNACYP1A2CYP2C19SMN1; SMN2HIF1A | |
| SCHEMBL8599075 | 0.73 | MAOA (0.39) | RHEBLMNACYP1A2CYP2C19SMN1; SMN2 | |
| SCHEMBL8602948 | 0.72 | RXFP1 (0.52) | SMN1; SMN2HTR2AALDH1A1PSMD14 | |
| SCHEMBL8601195 | 0.71 | KMT2A (0.38) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8601909 | 0.70 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL8600722 | 0.70 | MAOA (0.43) | RHEBSMN1; SMN2 | |
| SCHEMBL8603706 | 0.68 | TYR (0.53) | LMNASMN1; SMN2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773449-A | BACTERICIDES FOR HELICOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 1998-06-30 | — | — | US | disclosed |
| EP-0786454-A1 | THIOQUINOLONE DERIVATIVE | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1997-07-30 | — | — | EP | disclosed |