Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 15/20 | 0.59 |
| ▸ | BCHE | P06276 | 10/20 | 0.55 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2458150 | 0.81 | ACHE (0.74) | ACHEBCHEPRMT6CYP2A6CYP2C19 | |
| SCHEMBL11198868 | 0.77 | ACHE (0.74) | ACHEBCHEPRMT6 | |
| SCHEMBL9637594 | 0.75 | PRMT6 (0.63) | ACHEBCHEPRMT6MYC | |
| SCHEMBL82414 | 0.73 | POLB (0.59) | ACHEBCHEPRMT6 | |
| SCHEMBL12655116 | 0.73 | ACHE (0.63) | ACHEBCHEPRMT6CYP2A6CYP2C19 | |
| SCHEMBL19322301 | 0.73 | ALDH1A1 (0.34) | ACHEBCHE | |
| SCHEMBL8011063 | 0.71 | ACHE (0.61) | ACHEBCHEPRMT6CYP2A6CYP2C19 | |
| SCHEMBL8409986 | 0.71 | ACHE (0.61) | ACHEBCHEPRMT6CYP2A6CYP2C19 | |
| SCHEMBL6419073 | 0.71 | ACHE (0.55) | ACHEBCHEPRMT6CYP2A6CYP2C19 | |
| SCHEMBL1733144 | 0.71 | ACHE (0.61) | ACHEBCHEPRMT6CYP2A6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750714-A | Process for the manufacture of related intermediates including cistofur | BRANTFORD CHEMICALS INC. (CA) | 1998-05-12 | — | — | US | disclosed |