Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6604832 | 0.79 | L3MBTL1 (0.64) | LMNAL3MBTL1MAPTTDP1NR4A2 | |
| SCHEMBL10913154 | 0.78 | BLM (0.45) | LMNA | |
| Benzoic Acid SCHEMBL4281002 | 0.76 | HDAC3 (0.50) | LMNAPKMMAPTNR4A2SMN1; SMN2 | |
| Benzoic Acid SCHEMBL4276854 | 0.76 | HDAC3 (0.50) | LMNAPKMMAPTNR4A2SMN1; SMN2 | |
| SCHEMBL8606146 | 0.75 | PTGS2 (0.41) | LMNAPKML3MBTL1MAPTTDP1 | |
| SCHEMBL5564617 | 0.75 | LMNA (0.39) | LMNAPKML3MBTL1MAPTTDP1 | |
| SCHEMBL5611318 | 0.74 | CA1 (0.44) | LMNA | |
| SCHEMBL5611322 | 0.74 | CA1 (0.44) | LMNA | |
| SCHEMBL12464189 | 0.74 | TDP1 (0.68) | LMNAL3MBTL1MAPTTDP1NR4A2 | |
| SCHEMBL31351852 | 0.73 | KMT2A (0.52) | LMNAPKML3MBTL1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832144-A1 | ACTIVE ENERGY RAY-CURABLE RESIN COMPOSITIONS, A CURED ARTICLE AND AN OPTICAL LENS OBTAINED THEREFROM, AND NOVEL (METH)ACRYLATE COMPOUNDS THEREFOR | U C B, S.A. (BE) | 1998-04-01 | — | — | EP | claimed |
| WO-1997000276-A1 | ACTIVE ENERGY RAY-CURABLE RESIN COMPOSITIONS, A CURED ARTICLE AND AN OPTICAL LENS OBTAINED THEREFROM, AND NOVEL (METH)ACRYLATE COMPOUNDS THEREFOR | UCB, S.A. (BE) | 1997-01-03 | — | — | WO | claimed |