Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7916436 | 0.79 | PTGS2 (0.47) | CES2CES1 | |
| SCHEMBL6475627 | 0.77 | CES2 (0.44) | LMNAALDH1A1MAPK1CES2CES1 | |
| SCHEMBL8606148 | 0.75 | LMNA (0.40) | LMNAALDH1A1MAPK1CES2CES1 | |
| SCHEMBL11866525 | 0.73 | ALDH1A1 (0.58) | LMNAALDH1A1MAPK1CES2CES1 | |
| SCHEMBL5699545 | 0.72 | ALDH1A1 (0.52) | LMNAALDH1A1MAPK1L3MBTL1MAPT | |
| SCHEMBL9654433 | 0.72 | ALDH1A1 (0.58) | LMNAALDH1A1MAPK1MAPTTDP1 | |
| SCHEMBL78385 | 0.72 | ALDH1A1 (0.58) | LMNAALDH1A1MAPK1MAPTTDP1 | |
| SCHEMBL31351853 | 0.72 | CES2 (0.68) | LMNAALDH1A1CES2CES1L3MBTL1 | |
| SCHEMBL17867451 | 0.72 | L3MBTL1 (0.71) | LMNAL3MBTL1MAPTTDP1KMT2A | |
| SCHEMBL1122004 | 0.72 | L3MBTL1 (0.71) | LMNAL3MBTL1MAPTTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070093576-A1 | Reinforced coatings with improved scratch resistance | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2007-04-26 | — | — | US | disclosed |
| EP-1575895-A1 | PHENOLIC ANTIOXIDANTS IN CRYSTALLINE FORM | Ciba SC Holding AG (CH) | 2005-09-21 | — | — | EP | disclosed |
| EP-1532196-A1 | METHOD OF PRODUCING COLOURED PLASTICS OR POLYMERIC COLOUR PARTICLES | Ciba SC Holding AG (CH) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004048312-A1 | PHENOLIC ANTIOXIDANTS IN CRYSTALLINE FORM | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-06-10 | — | — | WO | disclosed |
| WO-2004020505-A1 | METHOD OF PRODUCING COLOURED PLASTICS OR POLYMERIC COLOUR PARTICLES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-03-11 | — | — | WO | disclosed |