SCHEMBL860722

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL466310	1.00	MEN1 (0.63)	MEN1KMT2AGRM4HDAC6KDM4E
	(Z)-1,2-Diphenylethene SCHEMBL3198659	0.78	CYP11B1 (0.54)	MEN1KMT2AGRM4HDAC6KDM4E
	SCHEMBL11381421	0.78	MEN1 (1.00)	MEN1KMT2AGRM4HDAC6KDM4E
	(Z)-1,2-Diphenylethene SCHEMBL529988	0.78	CYP11B1 (0.54)	MEN1KMT2AGRM4HDAC6KDM4E
	SCHEMBL11381426	0.78	MEN1 (1.00)	MEN1KMT2AGRM4HDAC6KDM4E
	(Z)-1,2-Diphenylethene SCHEMBL7755679	0.78	CYP11B1 (0.54)	MEN1KMT2AGRM4HDAC6KDM4E
	SCHEMBL6340037	0.78	MEN1 (0.65)	MEN1KMT2AGRM4HDAC6KDM4E
	SCHEMBL6340035	0.78	MEN1 (0.65)	MEN1KMT2AGRM4HDAC6KDM4E
	SCHEMBL29472997	0.77	MEN1 (0.64)	MEN1KMT2AGRM4HDAC6KDM4E
	SCHEMBL4077027	0.77	MAPT (0.57)	KDM4ENPC1RAB9ALMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.