Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25169259 | 0.79 | CA2 (0.42) | CA2CA4CA5ATDP1ALDH1A1 | |
| SCHEMBL13459606 | 0.76 | HDAC1 (0.46) | CA2CA4CA5ATDP1ALDH1A1 | |
| SCHEMBL20379780 | 0.75 | CA2 (0.33) | CA2CA4CA5A | |
| SCHEMBL28952122 | 0.71 | TRPV4 (0.48) | CA2CA4CA5A | |
| SCHEMBL25221122 | 0.71 | KCNQ3 (0.39) | CA2CA4CA5A | |
| SCHEMBL28101005 | 0.71 | NNMT (0.49) | ALDH1A1LMNA | |
| SCHEMBL2171752 | 0.71 | CA2 (0.71) | CA2CA4CA5ATDP1ALDH1A1 | |
| SCHEMBL1400873 | 0.70 | CA2 (0.54) | CA2CA4CA5AALDH1A1LMNA | |
| SCHEMBL29822627 | 0.70 | CA2 (0.54) | CA2CA4CA5AALDH1A1LMNA | |
| SCHEMBL17773854 | 0.70 | KDM4E (0.52) | CA2CA4CA5ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5716964-A | BRAIN DISORDERS; ANTIISCHEMIC AGENTS | G.D. SEARLE & CO. (US) | 1998-02-10 | — | — | US | disclosed |