Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16554273 | 0.74 | NNMT (0.33) | NNMTMKNK1MKNK2KMT2AMEN1 | |
| SCHEMBL13459606 | 0.74 | HDAC1 (0.46) | KMT2AKDM4EALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL28101008 | 0.73 | L3MBTL1 (0.53) | NNMTKMT2AMEN1KDM4ERAB9A | |
| SCHEMBL25169259 | 0.73 | CA2 (0.42) | ALDH1A1LMNA | |
| SCHEMBL8607426 | 0.71 | CA2 (0.41) | ALDH1A1LMNA | |
| SCHEMBL7790660 | 0.69 | FDFT1 (0.65) | KMT2AMEN1KDM4EMAPTRAB9A | |
| SCHEMBL2154730 | 0.69 | NNMT (0.68) | NNMTMKNK1MKNK2KMT2AMEN1 | |
| SCHEMBL233806 | 0.69 | CA2 (0.52) | RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL31435885 | 0.69 | — | — | |
| SCHEMBL18228074 | 0.68 | NNMT (0.72) | NNMTMKNK1MKNK2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105968136-A | Preparation method of aromatic phosphonate compound | 北京大学 | 2016-09-28 | — | — | CN | disclosed |