Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8607672 | 0.73 | L3MBTL1 (0.34) | TSHRKEAP1NFE2L2L3MBTL1MEN1 | |
| SCHEMBL7554537 | 0.68 | KMT2A (0.54) | L3MBTL1LMNAKMT2AMAPK1ALDH1A1 | |
| SCHEMBL7558733 | 0.67 | KMT2A (0.36) | TSHRKEAP1NFE2L2L3MBTL1KMT2A | |
| SCHEMBL7553096 | 0.66 | ALDH1A1 (0.38) | TSHRL3MBTL1MEN1LMNAKMT2A | |
| SCHEMBL27450361 | 0.66 | KMT2A (0.49) | TSHRL3MBTL1MEN1KMT2AALDH1A1 | |
| SCHEMBL8606545 | 0.66 | LMNA (0.40) | L3MBTL1LMNAKDM4EALDH1A1MGLL | |
| SCHEMBL7554588 | 0.60 | ALDH1A1 (0.36) | TSHRL3MBTL1MEN1LMNAKMT2A | |
| SCHEMBL7554590 | 0.60 | ALDH1A1 (0.36) | TSHRL3MBTL1MEN1LMNAKMT2A | |
| SCHEMBL4679853 | 0.59 | HTR2C (0.46) | — | |
| SCHEMBL7559631 | 0.59 | TP53 (0.39) | TSHRMEN1LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |