Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7558733 | 0.80 | KMT2A (0.36) | L3MBTL1KMT2ATSHRTP53MAPT | |
| SCHEMBL8606612 | 0.79 | LMNA (0.38) | GPBAR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8606657 | 0.74 | ALDH1A1 (0.45) | L3MBTL1GPBAR1KMT2AMAPK1MAPT | |
| SCHEMBL8607666 | 0.73 | TSHR (0.37) | L3MBTL1KMT2ATSHRMAPK1SMN1; SMN2 | |
| SCHEMBL7559631 | 0.71 | TP53 (0.39) | KMT2ATSHRTP53MAPTHTT | |
| SCHEMBL8607669 | 0.69 | STAT3 (0.44) | TSHRTP53SMN1; SMN2 | |
| SCHEMBL27448433 | 0.69 | HRH4 (0.34) | SMN1; SMN2KDM4EHTT | |
| SCHEMBL7554893 | 0.69 | GHSR (0.36) | GPBAR1KMT2AGHSRTSHRMAPK1 | |
| SCHEMBL7554537 | 0.68 | KMT2A (0.54) | L3MBTL1KMT2AMAPK1ALDH1A1 | |
| SCHEMBL7555638 | 0.67 | HRH4 (0.35) | KMT2ASMN1; SMN2KDM4EHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |