Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8606607 | 0.86 | LMNA (0.43) | LMNAEEDBCAT2CACNA1BSLC9A1 | |
| SCHEMBL8608708 | 0.74 | LMNA (0.38) | LMNAEEDBCAT2CACNA1BSLC9A1 | |
| SCHEMBL8608675 | 0.71 | LMNA (0.38) | LMNAEEDBCAT2CACNA1BSLC9A1 | |
| SCHEMBL8606547 | 0.70 | LMNA (0.39) | LMNAEEDBCAT2CACNA1BMMP2 | |
| SCHEMBL8494381 | 0.69 | LMNA (0.37) | LMNAEEDBCAT2CACNA1BSLC9A1 | |
| SCHEMBL8605528 | 0.68 | LMNA (0.42) | LMNAEEDBCAT2CACNA1BNAAA | |
| SCHEMBL8491954 | 0.68 | LMNA (0.36) | LMNAEEDBCAT2CACNA1BKDM4E | |
| SCHEMBL8607785 | 0.68 | LMNA (0.37) | LMNAEEDBCAT2CACNA1BSLC9A1 | |
| SCHEMBL8606612 | 0.67 | LMNA (0.38) | LMNAEEDBCAT2JAK2JAK1 | |
| SCHEMBL8489221 | 0.66 | SLC9A1 (0.40) | LMNAEEDCACNA1BSLC9A1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |