Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.43 |
| ▸ | NPC1 | O15118 | 9/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347241 | 0.88 | L3MBTL1 (0.51) | NPC1TP53L3MBTL1FFAR1FFAR4 | |
| SCHEMBL8608369 | 0.81 | L3MBTL1 (0.41) | RAB9ANPC1TP53MAPTLMNA | |
| SCHEMBL7778557 | 0.74 | L3MBTL1 (0.53) | NPC1TP53L3MBTL1FFAR1FFAR4 | |
| SCHEMBL28284271 | 0.73 | TSHR (0.42) | TP53LMNAL3MBTL1HTTTDP1 | |
| SCHEMBL2449732 | 0.72 | LIPG (0.49) | TP53MAPK1 | |
| SCHEMBL7346161 | 0.70 | L3MBTL1 (0.58) | TP53L3MBTL1KMT2AMEN1TDP1 | |
| SCHEMBL7336813 | 0.70 | FOLH1 (0.40) | MAPTLMNAHTTSMN1; SMN2KDM4E | |
| SCHEMBL26216122 | 0.70 | KDR (0.43) | TP53LMNAL3MBTL1HTTKMT2A | |
| SCHEMBL19951068 | 0.69 | ALDH1A1 (0.51) | RAB9ANPC1MAPTLMNAL3MBTL1 | |
| SCHEMBL7347243 | 0.69 | L3MBTL1 (0.53) | LMNAL3MBTL1KMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832061-A1 | BENZAMIDE DERIVATIVES AND THEIR USE AS VASOPRESSIN ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-04-01 | — | — | EP | disclosed |