Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 known ✓ | P22894 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | OGT | O15294 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 7/20 | 0.34 |
| ▸ | MMP2 | P08253 | 6/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4559714 | 0.97 | LMNA (0.41) | LMNAMAPTKDM4EOGTUSP2 | |
| SCHEMBL137702 | 0.97 | LMNA (0.41) | LMNAMAPTKDM4EOGTUSP2 | |
| SCHEMBL472442 | 0.76 | LMNA (0.41) | LMNAMAPTKDM4EOGTUSP2 | |
| SCHEMBL8609376 | 0.73 | LMNA (0.39) | LMNAMAPTKDM4EOGTUSP2 | |
| SCHEMBL8415310 | 0.67 | LMNA (0.59) | LMNAKDM4EMMP9MMP2TP53 | |
| SCHEMBL2873513 | 0.64 | — | — | |
| SCHEMBL4686843 | 0.63 | — | — | |
| SCHEMBL472532 | 0.62 | LMNA (0.41) | LMNAMAPTKDM4EOGTUSP2 | |
| SCHEMBL1980551 | 0.62 | LMNA (0.41) | LMNAMAPTKDM4EOGTUSP2 | |
| SCHEMBL17294203 | 0.59 | MMP9 (0.39) | LMNAMAPTMMP9MMP2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12552882-B2 | Polymeric disinfectants and uses thereof | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2026-02-17 | — | — | US | disclosed |
| EP-4237493-B1 | POLYMERIC DISINFECTANTS AND USES THEREOF | TECHNION RES & DEV FOUNDATION (IL) | 2025-12-10 | — | — | EP | disclosed |
| US-20230399423-A1 | POLYMERIC DISINFECTANTS AND USES THEREOF | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2023-12-14 | — | — | US | disclosed |
| EP-4237493-A1 | POLYMERIC DISINFECTANTS AND USES THEREOF | Technion Research & Development Foundation Ltd. (IL) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022091091-A1 | POLYMERIC DISINFECTANTS AND USES THEREOF | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2022-05-05 | — | — | WO | disclosed |
| US-10035752-B2 | Multifunctional (meth)acrylate manufacturing method | TOAGOSEI CO., LTD. (JP) | 2018-07-31 | — | — | US | disclosed |
| US-20170204044-A1 | MULTIFUNCTIONAL (METH)ACRYLATE MANUFACTURING METHOD | TOAGOSEI CO., LTD. (JP) | 2017-07-20 | — | — | US | disclosed |
| EP-3133058-A1 | MULTIFUNCTIONAL (METH)ACRYLATE MANUFACTURING METHOD | Toagosei Co., Ltd. (JP) | 2017-02-22 | — | — | EP | disclosed |
| US-7811397-B2 | Gas generating agent | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2010-10-12 | — | — | US | disclosed |
| US-20060065338-A1 | Gas generating agent | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2006-03-30 | — | — | US | disclosed |
| US-3725557-A | ALLOXANTIN COMPOUNDS AS ANTIBACTERIAL AND ANTIFUNGAL AGENTS | GATES RUBBER CO | 1973-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10035752-B2 | Multifunctional (meth)acrylate manufacturing method | MMAB, AMD1, ADH5 | MMP8 4199/4885LMNA 4637/4885MAPT 3989/4885 |
| US-12552882-B2 | Polymeric disinfectants and uses thereof | PIK3C3, POLR1C, CUTA | MMP8 1048/4885LMNA 1831/4885MAPT 4851/4885 |
| US-20170204044-A1 | MULTIFUNCTIONAL (METH)ACRYLATE MANUFACTURING METHOD | MMAB, AMD1, ADH5 | MMP8 4199/4885LMNA 4637/4885MAPT 3989/4885 |
| US-20230399423-A1 | POLYMERIC DISINFECTANTS AND USES THEREOF | CUTA, PRKDC, PIK3C3 | MMP8 1454/4885LMNA 4582/4885MAPT 4658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.