Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9234597 | 0.98 | HDAC3 (0.33) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL12430010 | 0.82 | DGAT1 (0.38) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8610290 | 0.76 | GAA (0.40) | — | |
| SCHEMBL12914653 | 0.76 | ADRA2A (0.38) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8611167 | 0.75 | ALDH1A1 (0.43) | — | |
| SCHEMBL12914655 | 0.74 | RECQL (0.35) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL24668232 | 0.72 | STING1 (0.37) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL917567 | 0.72 | STING1 (0.37) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL916562 | 0.72 | STING1 (0.37) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL20921788 | 0.72 | DGAT1 (0.38) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656349-B1 | Amidinophenol derivatives having phospholipase A2 inhibitory activity | ONO PHARMACEUTICAL CO (JP) | 1998-04-08 | — | — | EP | claimed |