Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8612267 | 0.81 | HSP90AA1 (0.40) | MEN1KMT2A | |
| SCHEMBL8611380 | 0.81 | KMT2A (0.38) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL8723999 | 0.76 | CYP3A4 (0.44) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL2322069 | 0.74 | ALDH1A1 (0.46) | BAZ2BBAZ2AMEN1KMT2A | |
| SCHEMBL30422061 | 0.74 | ALDH1A1 (0.46) | BAZ2BBAZ2AMEN1KMT2A | |
| SCHEMBL8610643 | 0.74 | RAB9A (0.43) | BAZ2BBAZ2AMEN1KMT2A | |
| SCHEMBL8615916 | 0.73 | KMT2A (0.41) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| Dimethylamine SCHEMBL8610644 | 0.71 | HSD17B10 (0.41) | ADAMTS4BAZ2BBAZ2AMEN1KMT2A | |
| SCHEMBL26267232 | 0.68 | HDAC1 (0.59) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL2483550 | 0.67 | HDAC1 (0.55) | HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789623-A | Process for the preparation of hydroxybiarylphosphines and novel compounds of this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |
| EP-0748811-A1 | Process for the preparation of hydroxybiarylphosphanes and novel compounds from this materials group | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-18 | — | — | EP | disclosed |