Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30422061 | 0.81 | ALDH1A1 (0.46) | RAB9AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2322069 | 0.81 | ALDH1A1 (0.46) | RAB9AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL20873225 | 0.80 | ALDH1A1 (0.50) | RAB9AALDH1A1MEN1KMT2ANPC1 | |
| Dimethylamine SCHEMBL8610644 | 0.78 | HSD17B10 (0.41) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL8611685 | 0.78 | RRM1 (0.43) | RAB9AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8615984 | 0.78 | RRM1 (0.41) | RAB9AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL20642035 | 0.75 | ALDH1A1 (0.44) | RAB9AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL8610345 | 0.74 | HDAC1 (0.38) | MEN1KMT2ABAZ2BBAZ2A | |
| SCHEMBL135145 | 0.70 | TDP1 (0.57) | RAB9AALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9838144 | 0.70 | TDP1 (0.57) | RAB9AALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789623-A | Process for the preparation of hydroxybiarylphosphines and novel compounds of this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |
| EP-0748811-A1 | Process for the preparation of hydroxybiarylphosphanes and novel compounds from this materials group | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-18 | — | — | EP | disclosed |