Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611380 | 0.89 | KMT2A (0.38) | KMT2AMEN1MAPTKDM4ETDP1 | |
| SCHEMBL8612267 | 0.89 | HSP90AA1 (0.40) | KMT2AMEN1MAPTKDM4ETDP1 | |
| SCHEMBL4004222 | 0.78 | PTPN22 (0.44) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL6928512 | 0.78 | PTPN22 (0.44) | KMT2AMEN1MAPTKDM4EALDH1A1 | |
| SCHEMBL8613770 | 0.78 | RRM1 (0.45) | KMT2AMEN1MAPTKDM4ETDP1 | |
| SCHEMBL7590618 | 0.73 | MAPT (0.43) | KMT2AMEN1MAPTKDM4ETDP1 | |
| SCHEMBL8610345 | 0.73 | HDAC1 (0.38) | KMT2AMEN1HDAC1HDAC8HDAC6 | |
| SCHEMBL8611033 | 0.72 | MAPT (0.47) | KMT2AMEN1MAPTKDM4ETDP1 | |
| SCHEMBL8723999 | 0.70 | CYP3A4 (0.44) | KMT2AMEN1TDP1ALDH1A1HDAC1 | |
| SCHEMBL7902294 | 0.70 | GAA (0.39) | TDP1ALDH1A1GAACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789623-A | Process for the preparation of hydroxybiarylphosphines and novel compounds of this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |
| EP-0748811-A1 | Process for the preparation of hydroxybiarylphosphanes and novel compounds from this materials group | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-18 | — | — | EP | disclosed |