Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RRM1 | P23921 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.35 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8613770 | 0.87 | RRM1 (0.45) | RRM1MAPTIDO1NSD2OPRM1 | |
| SCHEMBL8611516 | 0.85 | NSD2 (0.44) | NSD2OPRM1OPRD1HKDC1GAA | |
| SCHEMBL8615984 | 0.85 | RRM1 (0.41) | RRM1MAPTIDO1NSD2OPRM1 | |
| Dimethylamine SCHEMBL8611687 | 0.83 | HSP90AA1 (0.41) | MAPTNSD2OPRM1OPRD1HKDC1 | |
| SCHEMBL8611708 | 0.83 | HSP90AA1 (0.49) | MAPTNSD2OPRM1OPRD1HKDC1 | |
| SCHEMBL635353 | 0.81 | ALOX5 (0.40) | RRM1MAPTIDO1TDP1GAA | |
| SCHEMBL8612267 | 0.79 | HSP90AA1 (0.40) | MAPTNSD2OPRM1OPRD1HKDC1 | |
| Hydrochloric Acid SCHEMBL16561297 | 0.78 | MAPT (0.40) | RRM1MAPTIDO1TDP1GAA | |
| SCHEMBL8610643 | 0.78 | RAB9A (0.43) | MAPTTDP1GAAALDH1A1KDM4E | |
| SCHEMBL8609119 | 0.74 | NSD2 (0.48) | MAPTNSD2OPRM1OPRD1HKDC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789623-A | Process for the preparation of hydroxybiarylphosphines and novel compounds of this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |
| EP-0748811-A1 | Process for the preparation of hydroxybiarylphosphanes and novel compounds from this materials group | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-18 | — | — | EP | disclosed |