Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylmethane SCHEMBL4361124 | 0.65 | CALM1 (1.00) | CALM1LMNATSHRALDH1A1BCL2 | |
| Diphenylmethane SCHEMBL3792579 | 0.65 | CALM1 (1.00) | CALM1LMNATSHRALDH1A1BCL2 | |
| Diphenylmethane SCHEMBL28172316 | 0.65 | CALM1 (1.00) | CALM1LMNATSHRALDH1A1BCL2 | |
| Diphenylmethane SCHEMBL14763944 | 0.65 | CALM1 (1.00) | CALM1LMNATSHRALDH1A1BCL2 | |
| Diphenylmethane SCHEMBL1303 | 0.65 | CALM1 (1.00) | CALM1LMNATSHRALDH1A1BCL2 | |
| SCHEMBL4368908 | 0.64 | CALM1 (0.46) | CALM1TAAR1LMNACYP2D6CYP1A2 | |
| Diphenylmethane SCHEMBL28072604 | 0.63 | CALM1 (0.80) | CALM1LMNASIGMAR1BCL2BCL2L1 | |
| SCHEMBL1923108 | 0.62 | CALM1 (0.58) | CALM1TAAR1LMNACYP2D6CYP1A2 | |
| SCHEMBL2681077 | 0.62 | CALM1 (0.44) | CALM1TAAR1TSHRALDH1A1RAB9A | |
| SCHEMBL7776289 | 0.62 | ALDH1A1 (0.36) | SIGMAR1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937046-A2 | SUBSTITUTED 3-BENZYLPYRAZOLES AND THEIR USE AS HERBICIDES AND FOR LOWERING THE SUGAR CONTENT IN BLOOD | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-25 | — | — | EP | claimed |
| WO-1998020000-A2 | SUBSTITUTED 3-BENZYLPYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-05-14 | — | — | WO | claimed |
| EP-0937046-A2 | SUBSTITUTED 3-BENZYLPYRAZOLES AND THEIR USE AS HERBICIDES AND FOR LOWERING THE SUGAR CONTENT IN BLOOD | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-25 | — | — | EP | disclosed |
| WO-1998020000-A2 | SUBSTITUTED 3-BENZYLPYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-05-14 | — | — | WO | disclosed |