Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28508834 | 0.80 | DAO (0.39) | DAOTAAR1KMT2AALDH1A1MEN1 | |
| SCHEMBL3452798 | 0.76 | MAOA (0.32) | MAOBMAOADAO | |
| SCHEMBL2339223 | 0.65 | CALM1 (0.42) | CALM1MAOBMAOAPTPN1DAO | |
| Diphenylmethane SCHEMBL3792579 | 0.65 | CALM1 (1.00) | CALM1MAOBHPGDALDH1A1TSHR | |
| Diphenylmethane SCHEMBL14763944 | 0.65 | CALM1 (1.00) | CALM1MAOBHPGDALDH1A1TSHR | |
| Diphenylmethane SCHEMBL1303 | 0.65 | CALM1 (1.00) | CALM1MAOBHPGDALDH1A1TSHR | |
| Diphenylmethane SCHEMBL28172316 | 0.65 | CALM1 (1.00) | CALM1MAOBHPGDALDH1A1TSHR | |
| Diphenylmethane SCHEMBL4361124 | 0.65 | CALM1 (1.00) | CALM1MAOBHPGDALDH1A1TSHR | |
| SCHEMBL2515239 | 0.64 | MAOA (0.69) | CALM1MAOBMAOAPTPN1DAO | |
| SCHEMBL4368908 | 0.64 | CALM1 (0.46) | CALM1TAAR1HRH3KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12622856-B2 | Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer | HENKEL AG & CO. KGAA (DE) | 2026-05-12 | — | — | US | claimed |
| US-20250009629-A1 | AGENT FOR OXIDATIVE DYEING OF KERATIN FIBERS, CONTAINING ISATIN AND AT LEAST ONE DEFINED POLYMER | HENKEL AG & CO. KGAA (DE) | 2025-01-09 | — | — | US | claimed |
| US-6682572-B2 | READY-TO-USE HAIR DYES WITH C4-C8 ETHER OF AN ETHYLENE GLYCOL AND/OR C1-C8 ETHER OF A | L'OREAL S.A. (FR) | 2004-01-27 | — | — | US | claimed |
| EP-0998258-B1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES | OREAL (FR) | 2003-05-02 | — | — | EP | claimed |
| US-20020013971-A1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES | MAUBRU MIREILLE (FR) | 2002-02-07 | — | — | US | claimed |
| US-4333730-A | HAIR DYES | SOCIETE ANONYME DITE: L'OREAL (FR) | 1982-06-08 | — | — | US | claimed |
| US-4324553-A | OXIDATION COLOR DYES | L'OREAL (FR) | 1982-04-13 | — | — | US | claimed |
| US-4323360-A | Dyeing compositions for hair which contain 2,4-diamino-butoxybenzene and/or a salt thereof as the coupling agent | L'OREAL (FR) | 1982-04-06 | — | — | US | claimed |
| US-20240050343-A1 | COMPOSITION COMPRISING THE COMBINATION OF TWO PARTICULAR OXIDATION DYE PRECURSORS, AN ALKYL(POLY)GLYCOSIDE AND A SULFATED ANIONIC SURFACTANT | L'ORÉAL (FR) | 2024-02-15 | — | — | US | disclosed |
| US-11147754-B2 | Powder composition comprising hair direct dyes | KAO CORPORATION (JP) | 2021-10-19 | — | — | US | disclosed |
| US-20200197269-A1 | POWDER COMPOSITION COMPRISING HAIR DIRECT DYES | KAO CORPORATION (JP) | 2020-06-25 | — | — | US | disclosed |
| US-20200048468-A1 | POLYMERIC HAIR COLOR COMPOSITION | MILBOCKER MICHAEL (US) | 2020-02-13 | — | — | US | disclosed |
| WO-2020033501-A1 | POLYMERIC HAIR COLOR COMPOSITION | MILBOCKER MICHAEL (US) | 2020-02-13 | — | — | WO | disclosed |
| US-20170281501-A1 | 4,5-DIAMINOIMIDAZOLES AS NOVEL DEVELOPER-TYPE OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2017-10-05 | — | — | US | disclosed |
| US-20020013971-A1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES | MAUBRU MIREILLE (FR) | 2002-02-07 | — | — | US | disclosed |
| US-RE35654-E | Mixed coupled azo pigments | ENGELHARD CORPORATION (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0656131-B1 | ELECTROSTATIC TONER CONTAINING A METAL COMPLEX COLORANT AS CHARGE STABILISER | BASF AG (DE) | 1997-10-29 | — | — | EP | disclosed |
| EP-0656131-A1 | ELECTROSTATIC TONER CONTAINING A METAL COMPLEX COLORANT AS CHARGE STABILISER. | BASF AG (DE) | 1995-06-07 | — | — | EP | disclosed |
| WO-1994004962-A1 | ELECTROSTATIC TONER CONTAINING A METAL COMPLEX COLORANT AS CHARGE STABILISER | BASF AKTIENGESELLSCHAFT (DE) | 1994-03-03 | — | — | WO | disclosed |
| US-5246494-A | MIXED COUPLED AZO PIGMENTS | ENGELHARD CORPORATION (US) | 1993-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170281501-A1 | 4,5-DIAMINOIMIDAZOLES AS NOVEL DEVELOPER-TYPE OXIDATION DYE PRECURSORS | KRT18, DHODH, AOC1 | CALM1 2543/4885MAOB 212/4885MAOA 110/4885 |
| US-12622856-B2 | Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer | KRT18, ARSA, MKI67 | CALM1 445/4885MAOB 540/4885MAOA 813/4885 |
| US-20020013971-A1 | OXIDATION DYEING COMPOSITION FOR KERATIN FIBRES | KRT18, COX6C, MT-CO1 | CALM1 2470/4885MAOB 698/4885MAOA 541/4885 |
| US-20240050343-A1 | COMPOSITION COMPRISING THE COMBINATION OF TWO PARTICULAR OXIDATION DYE PRECURSORS, AN ALKYL(POLY)GLYCOSIDE AND A SULFATED ANIONIC SURFACTANT | KRT18, DSP, S100P | CALM1 4109/4885MAOB 743/4885MAOA 817/4885 |
| US-11147754-B2 | Powder composition comprising hair direct dyes | KRT18, DPM1, TYR | CALM1 1687/4885MAOB 1678/4885MAOA 1386/4885 |
| US-20250009629-A1 | AGENT FOR OXIDATIVE DYEING OF KERATIN FIBERS, CONTAINING ISATIN AND AT LEAST ONE DEFINED POLYMER | KRT18, TES, ARSA | CALM1 927/4885MAOB 471/4885MAOA 844/4885 |
| US-20200048468-A1 | POLYMERIC HAIR COLOR COMPOSITION | IK, CUTA, INCENP | CALM1 1473/4885MAOB 1131/4885MAOA 1290/4885 |
| US-20200197269-A1 | POWDER COMPOSITION COMPRISING HAIR DIRECT DYES | KRT18, DPM1, TYR | CALM1 1687/4885MAOB 1678/4885MAOA 1386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.