Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 8/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611019 | 0.81 | HSD17B10 (0.41) | TACR1CNR2CNR1PTPN5ALDH1A1 | |
| SCHEMBL8610662 | 0.81 | HNF4A (0.44) | ALDH1A1BACE1HNF4AHDAC4HDAC2 | |
| SCHEMBL6251039 | 0.75 | TSHR (0.42) | TACR1CNR2CNR1ALDH1A1 | |
| SCHEMBL25060877 | 0.75 | P2RX1 (0.43) | TACR1CNR2CNR1PTPN5ALDH1A1 | |
| SCHEMBL29669727 | 0.74 | ADORA2A (0.46) | CNR2PTPN5ALDH1A1RORCRORB | |
| SCHEMBL16311885 | 0.73 | AR (0.44) | TACR1CNR2CNR1PTPN5ALDH1A1 | |
| SCHEMBL8613773 | 0.73 | P2RX1 (0.39) | CNR2CNR1 | |
| SCHEMBL29163069 | 0.71 | HNF4A (0.47) | ALDH1A1BACE1HNF4AHDAC4HDAC2 | |
| SCHEMBL21040615 | 0.70 | KIF11 (0.52) | ALDH1A1BACE1 | |
| SCHEMBL9487300 | 0.70 | HDAC4 (0.62) | ALDH1A1BACE1HNF4AHDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789623-A | Process for the preparation of hydroxybiarylphosphines and novel compounds of this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |
| EP-0748811-A1 | Process for the preparation of hydroxybiarylphosphanes and novel compounds from this materials group | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-18 | — | — | EP | disclosed |