Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 10/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 9/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8611244 | 0.87 | P2RX1 (0.41) | P2RX1P2RX3P2RX4P2RX7NSD2 | |
| SCHEMBL8615377 | 0.85 | P2RX1 (0.39) | P2RX1P2RX3P2RX4P2RX7NSD2 | |
| SCHEMBL8611516 | 0.81 | NSD2 (0.44) | NSD2OPRM1OPRD1HKDC1HSP90AA1 | |
| SCHEMBL2229892 | 0.81 | P2RX1 (0.40) | P2RX1P2RX3P2RX4P2RX7CNR1 | |
| SCHEMBL30391892 | 0.81 | P2RX1 (0.40) | P2RX1P2RX3P2RX4P2RX7CNR1 | |
| SCHEMBL5083753 | 0.81 | P2RX1 (0.36) | P2RX1P2RX3P2RX4P2RX7CNR2 | |
| SCHEMBL8611708 | 0.79 | HSP90AA1 (0.49) | NSD2OPRM1OPRD1HKDC1HSP90AA1 | |
| SCHEMBL8611019 | 0.78 | HSD17B10 (0.41) | P2RX1P2RX4P2RX7CNR1CNR2 | |
| Dimethylamine SCHEMBL8611687 | 0.76 | HSP90AA1 (0.41) | NSD2OPRM1OPRD1HKDC1HSP90AA1 | |
| SCHEMBL30616088 | 0.75 | KCNQ3 (0.34) | P2RX1P2RX3P2RX4P2RX7CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789623-A | Process for the preparation of hydroxybiarylphosphines and novel compounds of this group of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-08-04 | — | — | US | disclosed |
| EP-0748811-A1 | Process for the preparation of hydroxybiarylphosphanes and novel compounds from this materials group | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-12-18 | — | — | EP | disclosed |